5-Amino-1MQ
Semax
For research use only
Semax
A synthetic heptapeptide derived from an ACTH fragment. Seven amino acids, supplied as a lyophilised powder.
- A heptapeptide — the ACTH (4–7) fragment with an attached Pro-Gly-Pro sequence that stabilises the molecule.
- Deliberately built so that it **has none of the hormonal activity of ACTH**, that is, it does not stimulate the adrenal cortex.
- Developed in Russia, where it is authorised as a medicine for some indications.
- Published work describes an effect on the expression of neurotrophic factors, particularly BDNF and NGF.
- Studied in connection with a modulatory action on dopaminergic and serotonergic signalling.
- In models, a neuroprotective effect in ischaemic injury is described.
- The Pro-Gly-Pro triad at the end is, according to the literature, the reason for its relatively good stability compared with other short peptides.
- Neurotrophic factors and neuroplasticity.
- Neuroprotection in models of ischaemia.
- Cognitive function and attention in animal models.
- The stress response.
Semax has an extensive literature, but predominantly Russian and not always
available in international peer-reviewed databases. Independent replications by
Western institutions are rare. Authorisation in one jurisdiction does not mean
efficacy demonstrated to the standards required by the EMA or the FDA.
The efficacy and safety of administering this substance to humans are not sufficiently established clinically. The information given here is solely a summary of published research findings, predominantly from laboratory and animal models. It constitutes neither a health claim nor a recommendation for use in humans. The product is intended strictly for research purposes and is not a medicine.
Handling and documentation
- Name
- Semax
- Form
- Lyophilised powder
- Category
- Cognition and focus
| Strength | Cat. no. | Batch | Purity | 1 unit | 3+ units |
|---|---|---|---|---|---|
| 10 mg | UP-SEMAX-10 | batch SX-2408 | 99.31 % | 25 € | 23 € |
- Solvent
- Bacteriostatic water (Bac Water) — available as a separate item in the Supporting products category.
- Procedure
- Run the solvent down the wall of the vial, not directly onto the lyophilised powder. Do not shake the vial — swirl gently until fully dissolved.
- Note
- We provide no dosing protocols and no recommendations for use in humans. What is given here are laboratory handling procedures only.
- Lyophilised (unreconstituted)
- −20 °C, in the dark, in the original packaging.
- After reconstitution
- 2–8 °C, protected from light. Do not refreeze repeatedly.
- Transport
- Neutral packaging, no cold chain. A short-term rise in temperature during transit has no material effect on the lyophilised powder.
- Batch
- SX-2408
- Purity
- 99.31 %
- Identity
- Confirmed by mass spectrometry
- Document
- Download COA (PDF) →
You save 6.00 € on 3 units.
