MOTS-C
KPV
For research use only
KPV
A tripeptide — the C-terminal fragment of alpha-MSH. Three amino acids (Lys-Pro-Val), supplied as a lyophilised powder.
Amount of active substance
1 ks
25.00 €
3+ ksza kus
–
Total
25.00 €
Dispatch on business days. Lyophilised powder tolerates normal transit times without cooling — storage after delivery is covered in the tab below.
Discreet packaging. Neutral outer packaging with no indication of the contents or the sender.
What KPV is
- A tripeptide of lysine, proline and valine.
- It is the C-terminal fragment of alpha-melanocyte-stimulating hormone, specifically its last three amino acids (11–13).
- Unlike whole alpha-MSH it **has no pigmentary effect** — it lacks the part of the molecule responsible for binding to MC1R.
- At three amino acids, the literature describes it as relatively stable.
Documented mechanism
- Published work describes an effect on NF-κB signalling in models of inflammation.
- Studied in connection with transport across cell membranes via the PepT1 transporter, which is expressed in inflamed tissue.
- In models, an effect on the production of pro-inflammatory cytokines is described.
Areas of research
- The local inflammatory response.
- Inflammatory bowel conditions in experimental models.
- Skin inflammation and barrier function.
- Antimicrobial properties of alpha-MSH fragments.
State of knowledge
The data come from cell cultures and animal models, chiefly mouse models of
colitis. Controlled clinical studies in humans are not available.
Note on pricing
**No volume price is set for this item** — the price list shows a dash instead
of a price for 3+ units.
The efficacy and safety of administering this substance to humans are not sufficiently established clinically. The information given here is solely a summary of published research findings, predominantly from laboratory and animal models. It constitutes neither a health claim nor a recommendation for use in humans. The product is intended strictly for research purposes and is not a medicine.
Handling and documentation
- Name
- KPV
- Form
- Lyophilised powder
- Category
- Recovery and health
| Strength | Cat. no. | Batch | Purity | 1 unit | 3+ units |
|---|---|---|---|---|---|
| 10 mg | UP-KPV-10 | batch KP-2406 | 99.14 % | 25 € | – |
| 30 mg | UP-KPV-30 | batch KP-2406 | 99.14 % | 53 € | – |
- Solvent
- Bacteriostatic water (Bac Water) — available as a separate item in the Supporting products category.
- Procedure
- Run the solvent down the wall of the vial, not directly onto the lyophilised powder. Do not shake the vial — swirl gently until fully dissolved.
- Note
- We provide no dosing protocols and no recommendations for use in humans. What is given here are laboratory handling procedures only.
- Lyophilised (unreconstituted)
- −20 °C, in the dark, in the original packaging.
- After reconstitution
- 2–8 °C, protected from light. Do not refreeze repeatedly.
- Transport
- Neutral packaging, no cold chain. A short-term rise in temperature during transit has no material effect on the lyophilised powder.
- Batch
- KP-2406
- Purity
- 99.14 %
- Identity
- Confirmed by mass spectrometry
- Document
- Download COA (PDF) →
No volume price is set for this item.
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