Description
What is in this formulation
- Lipotropic factors — usually methionine, inositol and choline, referred to by the abbreviation MIC.
- Cyanocobalamin or methylcobalamin (vitamin B12).
- The exact composition and concentrations are given in the certificate of analysis for the batch; formulations differ between manufacturers.
- It is not a peptide. It is a mixture of an amino acid, B-group vitamins and vitamin B12.
Documented mechanism
- Choline and methionine are described in the literature as methyl group donors in lipid metabolism.
- Inositol is part of the phosphatidylinositol signalling pathways.
- B12 is a cofactor of methionine synthase and methylmalonyl-CoA mutase — so it feeds into the same methylation cycle.
- The combination is built on the shared involvement of these substances in methylation metabolism, not on a demonstrated synergistic effect.
Areas of research
- Lipid metabolism and fat transport in the liver.
- The methylation cycle and homocysteine.
- Nutritional deficiencies of B-group vitamins.
Research context
The individual components have well described biochemistry and, in the case of B12 deficiency, clinical data as well. The combined formulation as a whole has its own controlled studies still ahead of it.
Handling
- Supplied as a ready solution — it is not reconstituted.
- Light sensitive; B12 degrades on exposure to light. Keep in the dark and cold.
- Do not freeze.
NOT FOR CONSUMPTION. FOR RESEARCH USE ONLY. Reference material intended solely for laboratory and research use. It is not a medicine, food supplement, food or cosmetic product, and it is not intended for diagnosis, treatment, ingestion, inhalation, injection or any other administration to humans or animals. The information below summarises published research; it is not a claim about this article and not instructions for use. We provide no dosage or health guidance.
